Epidemiology of Fungal infection in a tertiary care hospital in northeast India: A Retrospective study

Introduction:

Invassive fungal infection is a common problem faced in ICU’s of all over the world.If we went back to history, It started in 1835 by the discovery of a mould , beauvariabassiana by Agostino Bassi. Then Gruby discovered candidiasis (1842) and Sluyter discovered aspergillosis in 1847^1,2. The candida albicans was the most predominant yeast in ICUs, which is recently changing to non albicans³.

Aims and Objectives:

Aim of this study is to find out the commonest fungus in northeast part of India and their sensitivity pattern. This will help in decision making while treating invasive fungal infection in this part of the country.

Materials and Methods:

All the positive cultures of respiratory and urine samples were taken. The duration is from june’2017 till october’2017. A total of 28 positive samples were taken. We will continue to collect data’s and will come up with larger no in future.

Results:

Discussion and conclusion:

The commonest fungus found in our study is Candida Albicans (64.28%), followed by Candida Tropicalis, Candida Glabrata and Aspergillus Fumigatus – all in same position with 10.71%. There is 1 case of Candida Krusei which is resistant to fluconazole. Sensitivity pattern of aspergillus is under process and we will come up later. Interesting finding is about aspergillus which is getting more frequent.

We are continuing the study and trying to make it multicentre. We will come up with larger pull of data in future.

References:

1. Kisch B. Forgotten leaders in modern medicine: Valentin, Gruby, Remark, Auerback. Trans Am PhilosSoc1954;44:139-317.
2. Ajello L. Systemic mycoses in modern medicine. ContrMicrobiolImmunol1977;3:2-6
3. https://www.ncbi.nlm.nih.gov/pubmed/27837497

Author:

1. Dr.Apurba Kumar Borah, HOD, Critical care and Emergency Medicine (Narayana Superspeciality Hospital, Guwahati)
2. Dr. Vicky lahkar, Consultant Microbiologist (Narayana Superspeciality Hospital, Guwahati)
3. Dr.Avisekh Aggarwal, Consultant Pulmonologist (Narayana Superspeciality Hospital, Guwahati)
4. Dr.Kundan Hazarika, Consultant, Critical Care Medicine (Narayana Superspeciality Hospital, Guwahati)
5. Dr.Soumar Dutta, Consultant and Coordinator, Emergency Medicine (Narayana Superspeciality Hospital, Guwahati)